Pyrin and HIN Domain Family, Member 1 (PYHIN1) Peptide
PYHIN1
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN936790
Aperçu rapide pour Pyrin and HIN Domain Family, Member 1 (PYHIN1) Peptide (ABIN936790)
Antigène
PYHIN1
(Pyrin and HIN Domain Family, Member 1 (PYHIN1))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- ANNYKKIVLL KGLEVINDYH FRIVKSLLSN DLKLNPKMKE EYDKIQIADL
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of PYHIN1 antibody,
Alternative Names: PYHIN1 control peptide, PYHIN1 antibody Blocking Peptide, Anti-PYHIN1 Blocking Peptide, pyrin and HIN domain family, member 1 Blocking Peptide, IFIX Blocking Peptide, MGC23885 Blocking Peptide, RP.1 Blocking Peptide, PYHIN1, PYHIN-1, PYHIN 1, PYHIN-1 Blocking Peptide, PYHIN 1 Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
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Sujet
- PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.
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Poids moléculaire
- 55 kDa
Antigène
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